4th Global Conference on Tissue Engineering and Regenerative Medicine, Stem Cell Research

Webinar

August 25-26, 2022

Scientific Program

Global assembling of Academicians, Researchers, Scholars & Industry to disseminate and exchange information at 100+ Allied Academics Conferences

Theme

Exploring Innovation in Tissue Engineering and Regenerative Medicine

- Regenerative Medicine 2022

About Conference

About Conference

The 4th Global Conference on Tissue Engineering and Regenerative Medicine, Stem Cell Research which is scheduled during August 25-26, 2022 virtually is focused on theme “Exploring innovation in Tissue Engineering and Regenerative Medicine” and to put forth the eminent research and development in eminent field of regenerative medicine and stem cells which the plays curial role in current and prospective technologies .The conference emphasizes on the vital role of stem cells and regenerative medicine in field of medicine and healthcare current trends in stem cell technology and future aspects of building the functional and infrastructural concept of stem cell therapy. Encompasses the spectrum of regenerative sciences from discovery to application and focuses on providing with understanding that spans traditional academic disciplines. It has innovative education experiences to produce the expert scientists needed to create the next generation of regenerative diagnostic and therapeutic solutions.

Regenerative medicine, the foremost recent and emerging branch of bioscience, deals with functional restoration of tissues or organs for the patient with severe injuries or chronic disease. The spectacular progress within the field of vegetative cell research has laid the inspiration for cell based therapies of disease which cannot be cured by conventional medicines. The indefinite self-renewal and potential to differentiate into other kinds of cells represent stem cells as frontiers of regenerative medicine. The Transdifferentiating potential of stem cells varies with source and consistent with that regenerative applications also change. Advancements in gene editing and tissue engineering technology have endorsed the ex vivo remodeling of stem cells grown into 3D organoids and tissue structures for personalized applications. This review outlines the foremost recent advancement in transplantation and tissue engineering technologies of ESCs, TSPSCs, MSCs, UCSCs, BMSCs, and iPSCs in regenerative medicine. Additionally, it also discusses stem cells regenerative application in wildlife conservation.

This conference plays a world platform for biomedical companies, start-ups, clinical research divisions, professionals, specialists, consultants, doctors, scholars and students to border new relationship and strengthen the Knowledge. This can be an excellent opportunity for all the delegates from Universities and Institutes to interact with the highest grade world class Scientists. The actual participants can confirm their participation through Registrations. To explore More Regarding the Recent Research in somatic cell its application attends Regentative Medicine 2022.

Welcome Message

With great delight and honor we invite the participants from all over the globe to take part in our annual flagship conference and explore your research and knowledge in our 4th Global Conference on Tissue Engineering and Regenerative Medicine, Stem Cell Research which is scheduled during August 25-26, 2022 virtually.

Sessions and Tracks

Track 1- Stem Cells and Development

Stem cells present in Human body are unspecialized cells. They have the power to differentiate into any cell in an organism and to regenerate. Stem cells exist both in embryos and adult cells. They are specialized into many stages. Each stage reduces its developmental potency, where its produces unipotent stem cell which can't differentiate into as many different types of cells as a pluripotent cells.

Adult stem cells
Adult cells altered to have properties of embryonic stem cells
Perinatal stem cells

Track 2- Tissue Engineering

Tissue engineering tries to use the self-healing characteristics of biological tissues to regenerate and restore organ function. To do so, cells from various origins, growth-inducing chemicals, and a biomaterial-support termed a scaffold are utilized alone or in combination to reconstruct organs. However, regenerating a functional tissue or organ has proven difficult. With recent advancements in adult and embryonic stem cell technologies, the fantasy of regenerating a full organ, or at least sections of it, appears to be closer than ever.

Bioartificial organs
Biomimetics
Long fiber generation

Track 3- Organ Regeneration

Organ re-construction can be done in vitro in laboratories and made available on demand, or in vivo using regenerative factors and a microenvironment that allows organs to grow inside the body. The combination of stem cells with tissue engineering has yielded significant advances, with the potential to usher in a paradigm change in regenerative medicine.

Implantation
Biopsy
Cell isolation
Scaffold

Track 4- 3D Bio-Printing and Organ Printing

Engineering, manufacturing, art, education, and medicine are just a few of the fields where three-dimensional (3D) printing is driving substantial changes. Biocompatible materials, cells, and supporting components can now be 3D printed into complex 3D functioning living tissues, thanks to recent advancements. To meet the demand for transplantable tissues and organs, 3D bio printing is being used in regenerative medicine. 3D bio printing has more complexities than non-biological printing, such as material selection, cell kinds, growth and differentiation variables, and technical obstacles associated to living cell sensitivities and tissue assembly. Engineering, biomaterials science, cell biology, physics, and medicine must all work together to solve these problems. Bio printing in 3D has already been used to create and test new drugs.

3D-bioprinted tissue models
Inkjet based 3D Bio printing
Extrusion based 3D Bio printing
Laser assisted 3D Bio printing
Stereolithographic based 3D Bio printing

Track 5- Embryonic Stem Cells as a Powerful Tool

Human embryonic stem cells (HESC) are pluripotent stem cell lines produced from human blastocyst-stage embryos' inner cell mass (ICM). They are defined by their culture's limitless ability for self-renewal. Furthermore, their ability to generate virtually any cell type in vivo and in vitro demonstrates their extensive developmental potential. HESC is tremendously essential in basic and practical research because of these two characteristics. They could also be an effective tool for understanding human development. By expressing developmentally controlled genes and activating biological pathways in the same way that they do in vivo, HESC can mimic embryogenesis. They can also be used to investigate the impact of individual mutations on specific developmental events, potentially allowing us to find crucial components.

Growth Factor–Induced Differentiation
Ectoderm Differentiation
Neuronal Differentiation
Mesoderm Differentiation

Track 6- Cancer and stem cells

Cancer Stem Cells (CSCs) are a small subpopulation of cells inside tumors with abilities of self-renewal, differentiation, and tumorigenicity while transplanted into an animal host. A variety of mobileular floor markers including CD44, CD24, and CD133 are regularly used to pick out and enhance CSCs. A regulatory community which includes microRNAs and Wnt/?-catenin, Notch, and Hedgehog signaling pathways controls the CSC properties. The medical relevance of CSCs has been bolstered with the aid of using rising evidence, demonstrating that CSCs are resistant to traditional chemotherapy and radiation remedy and that CSCs are very possibly to be the starting place of most cancers metastasis. CSCs are believed to be an critical goal for novel anti-most cancers drug discovery. Herein we summarize the present day expertise of CSCs, with a focal point at the function of miRNA and epithelial mesenchymal transition (EMT), and speak the medical software of concentrated on CSCs for most cancers remedy.

BMI-1
Notch
Sonic hedgehog and Wnt

Track 7- Stem cell therapy

Cell therapy involves the introduction of cells directly into the body for the purpose of healing. The therapeutic function propagates in single cell. For regenerative medicine, the ultimate goal of cell therapy is to establish a long-term transplant with the ability to carry out the organ's functions. A practical example is a bone marrow transplant, where HSCs are the therapeutic unit, which inserts the bone marrow and regenerates the whole blood stream.

Gene doping
Human genetic engineering
Treatment of genetic diseases

Track 8- Stem cells and tissue banks

Stem cell banking or preservation is the extraction, processing and storage of stem cells, which are stored and reserved for future prospective, when required. Stem Cell has power to regenerate into any tissue or organ in your body. It is due to this unique characteristic that they have the potential to treat over life threatening conditions, and provide numerous benefits to the baby, its siblings and the family.

Tissue banking
Tissue preservation
Tissue storage

Track 9- Biomaterials and Scaffold Design

A fundamental component of the regenerative endodontic process is the presence of a scaffold for stem cells from the apical papilla to adhere to, multiply and differentiate. The aim of this review is to provide an overview of the biomaterial scaffolds that have been investigated to support stem cells from the apical papilla in regenerative endodontic therapy and to identify potential biomaterials for future research.

Instructive scaffolds
Endodontic therapy
Blood-biomaterial interactions

Track 10 - Regenerative Medicine and Surgery

As the population ages, there is an increasing need for organ and tissue replacement to cope with the deterioration and disease of cardiovascular, gastrointestinal, kidney, and musculoskeletal organs. Transplantation of live and dead donor organs cannot currently meet this need. Regenerative medicine is an interdisciplinary field that incorporates stem cell biology, immunology, materials science, engineering, medicine, and surgery to develop solutions that can enhance or replace the regenerative capacity of the body's own tissues. With such a wide range of disciplines, it is important for different stakeholders to understand where the overall picture of the process of developing and clinically using regenerative medicine products fits. It also discusses recent surgical applications in regenerative medicine.

Hand transplantation
Face transplantation
Lymphedema
Preclinical modeling

Track 11 - COVID-19 and Convalescent Plasma

The use of convalescent plasma (CP) collected from the previously infected individuals to passively transfer antibodies as to guard or treat human’s dates back almost 100 years. Results from small cases series during the prior SARS and MERS coronavirus outbreaks suggested that the Convalescent Plasma is safe and should confer clinical benefits, including faster viral approval, particularly when administered early within the disease course1. The overwhelming majority of patients who get over COVID-19 illness develop circulating antibodies to varied SARS-CoV-2 proteins 2-3 weeks following infection, which are detectable by ELISA or other quantitative assays and sometimes correlate with the presence of neutralizing antibodies. Donations can occur as frequently as weekly for several months before antibody titers begin decreasing. Allowed donation frequency varies between blood centers. Listed below are some sites for referral of potential donors.

Track 12 - Techniques in stem cell research

Characterization of stem cell cultures has two main purposes. Monitoring the integrity of the cell's genome and tracking the expression of proteins associated with changes in pluripotency of epigenetic profiles. Proteome analysis ensures that cells express the factors necessary to maintain pluripotency. Confirmation of differentiation status by analysis of important genetic and protein markers ensures correct cell type identification and proliferation.

Stem cell characterization
Karyotyping
Fluorescence in situ hybridization (FISH)
Comparative genomic hybridization

Track 13- Hematopoietic stem cell transplantation

Hematopoietic stem cell transplantation (HSCT) is the intravenous infusion of hematopoietic stem cells to restore blood cell production in individuals with damaged or dysfunctional bone marrow or immune systems. This approach has been utilized to treat a variety of malignant and nonmalignant disorders with increasing frequency during the last half-century. Cells for HSCT can be taken from the patient (autologous transplant), a sibling or unrelated donor (allogeneic transplant), or an identical twin (allogeneic transplant) (syngeneic transplant). Bone marrow, peripheral blood, umbilical cord blood, and foetal liver are all possible cell sources.

Procurement of Stem Cells
Manipulation of Stem Cell Grafts
Preparative Regimens for HSCT
Infusion of Stem Cells and Engraftment

Market Analysis

Market Analysis

The field of regenerative medicine comprises of abundant strategies, which mainly includes the utilization of materials and de novo generated cells, also as various amalgamations therefore, to substitute the lost tissue, efficiently replacing it both anatomically and functionally, or to contribute to tissue restoration. The most objective of regenerative medicine is to propagate replacement tissue or organs for patients who have sustained an injury or have had a disease that permanently damaged their tissue. National Institutes of Health defines regenerative medicine as a process of making living, functional tissues to repair or replace tissue or organ function lost thanks to age, disease, damage, or congenital defects.

Regenerative Medicine Market Report Highlights

The therapeutics segment dominated the market in 2020 due to the high usage of primary cell-based therapies along with advances in stem cell and progenitor cell therapies. The implementation of these therapies in dermatological, musculoskeletal, and dental application results in the highest share of this segment
With the rise in R&D and clinical trials of regenerative medicines, key players are offering several consulting services leading to lucrative growth of the services segment
The oncology segment is estimated to account for the largest revenue share by 2027 owing to the high prevalence of cancer indications, which drives the demand for better solutions. The presence of a strong pipeline of regenerative medicines for cancer treatment also supplements the segment growth
North America dominated the market in 2020 and is projected to continue its dominance over the forecast period. A significant number of universities and research organizations investigating various stem cell-based approaches for regenerative apposition in the U.S. propels the region's growth
Asia Pacific is projected to witness the fastest CAGR over the forecast period due to the emergence of key players and rapid adoption of cell-based approaches in the healthcare